Our scientists design, develop and improve formulations and adjuvants for new vaccine candidates.


Our focus here is on developing a proper formulation that is suitable for the intended administration route, and also stable upon storage.  We test the stability of new formulations in accelerated, real-time and in-use stability studies using the appropriate set of assays.


Water-free vaccines

However, some vaccines are difficult to stabilize in a liquid formulation, especially if these vaccines contain live-attenuated viruses. To solve this, we have the facilities and expertise to develop water-free vaccine products (e.g. by lyophilization or spray-drying). We also apply drying techniques for the preparation of stable seed lots and reference materials.


Alternative administration

Furthermore, we are working on products for alternative routes of administration of vaccines than intramuscular administration (e.g. intranasal or mucosal routes)



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A team of 100+ specialists is at your disposal here in Bilthoven. Contact us to see how we can bring your vaccine concept ready for in-human trials.


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